RPS9

Across TCGA patient cohorts, RPS9 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS9-associated genes across cancer lineages are Lck, Notch1, and Tuberin. Each is linked with RPS9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS9-to-partner and partner-to-RPS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lck grouped by RPS9-low versus RPS9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS9→partner) and Y-score (partner→RPS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Lck →	+0.279	+3.000	.016	.037	3	1
UCEC	Notch1 →	+0.212	+2.817	.009	.036	3	1
UCEC	Tuberin →	+0.395	+3.000	.011	.037	3	1
UCEC	ATM →	-0.637	-3.000	.015	.037	3	1
UCEC	Di-Ras3 →	-0.245	-3.000	.004	.037	3	1
UCEC	eIF4E →	+0.330	+3.000	.006	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Lck by RPS9 expression — UCEC

Explore this box plot interactively →