RPS8

Across TCGA pan-cancer cohorts, RPS8 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RPS8 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RPS8 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS8 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

LSCC, CCRCC, and PDAC are the cancer types where RPS8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	1.000	0.851	.001	53	view →
CCRCC	DFS	Tertile	III,IV	0.472	0.757	.013	21	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	15	view →
UCEC	OS	Median	II,III,IV	1.000	0.628	.013	12	view →
LUAD	OS	Quartile	II,III,IV	0.261	0.839	.010	4	view →
GBM	DFS	Median	All	0.660	0.837	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPS8–LSCC (DFS)

Open the LSCC breakdown →