RPS8

Across TCGA cell cohorts, RPS8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,529 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPS8-associated GO terms across cancer lineages are Vacuolar transport, Endosomal transport, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with RPS8 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPS8-to-partner and partner-to-RPS8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by RPS8-low versus RPS8-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS8→partner) and Y-score (partner→RPS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Vacuolar transport →	-0.068	-0.738	<.001	<.001	3	13
BREAST	Endosomal transport →	-0.058	-0.904	.001	<.001	3	13
BONE	Multi-pass transmembrane protein insertion into ER membrane →	-0.131	-0.837	<.001	<.001	3	12
SKIN	Lysosome organization →	-0.061	-0.554	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Response to epidermal growth factor →	-0.112	-1.081	<.001	<.001	3	12
SKIN	Lytic vacuole organization →	-0.061	-0.554	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,529 associations by consensus.

Vacuolar transport by RPS8 expression — SKIN

Explore this box plot interactively →