RPS7

Across TCGA patient cohorts, RPS7 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS7-associated genes across cancer lineages are Notch1, p62 Lck ligand, and 14-3-3_zeta. Each is linked with RPS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS7-to-partner and partner-to-RPS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by RPS7-low versus RPS7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS7→partner) and Y-score (partner→RPS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.171	+3.009	.012	.019	3	1
UCEC	p62 Lck ligand →	+0.382	+3.009	.015	.019	3	1
UCEC	14-3-3_zeta →	-0.231	-2.432	.020	.020	3	1
UCEC	Cyclin-B1 →	+0.598	+2.459	.027	.020	3	1
UCEC	p27_pT198 →	+0.126	+3.000	.015	.036	2	1
UCEC	p90 RSK →	+0.281	+3.598	.002	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Notch1 by RPS7 expression — UCEC

Explore this box plot interactively →