Across TCGA cell cohorts, RPS6KL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,770 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RPS6KL1-associated GO terms across cancer lineages are Regulation of glucose mediated signaling pathway, Positive regulation of glucose mediated signaling pathway, and Transcription initiation at RNA polymerase III promoter. Each is linked with RPS6KL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPS6KL1-to-partner and partner-to-RPS6KL1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KL1→partner) and Y-score (partner→RPS6KL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of glucose mediated signaling pathway →	+0.143	+1.917	.001	<.001	3	8
LUNG_SCLC	Positive regulation of glucose mediated signaling pathway →	+0.143	+1.917	.001	<.001	3	8
LUNG_SCLC	Transcription initiation at RNA polymerase III promoter →	+0.117	+1.997	<.001	<.001	3	8
CNS	Positive regulation of telomerase RNA localization to Cajal body →	+0.067	+1.070	.001	<.001	3	8
CNS	Skin development →	-0.092	-0.921	<.001	.003	3	7
LUNG_SCLC	Regulation of DNA repair →	+0.048	+1.424	.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,770 associations by consensus.

Exploration

RPS6KL1 survival (RNA) · tumor vs normal (RNA) · all RPS6KL1 data types