Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, RPS6KL1 mutation is significantly associated with the RNA expression of many other genes, with 1,334 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.
The most reproducible RPS6KL1-associated genes across cancer lineages are MUC5B, FBXW10, and CBY1. Each is linked with RPS6KL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS6KL1-to-partner and partner-to-RPS6KL1 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (RPS6KL1→partner) and Y-score (partner→RPS6KL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.