RPS6KA5

Across TCGA patient cohorts, RPS6KA5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,729 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPS6KA5-associated genes across cancer lineages are PPP1R13B, GSTZ1, and GDAP1. Each is linked with RPS6KA5 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPS6KA5-to-partner and partner-to-RPS6KA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA5 versus PPP1R13B in LUAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA5→partner) and Y-score (partner→RPS6KA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPP1R13B →	+0.592	+0.383	<.001	<.001	3	7
BRCA	GSTZ1 →	+0.781	+0.562	<.001	<.001	3	6
BRCA	GDAP1 →	+0.875	+0.377	.006	.004	3	6
UCEC	GARS1 →	-0.480	-0.606	<.001	<.001	3	6
BRCA	ALDH6A1 →	+1.036	+0.543	<.001	<.001	3	6
LSCC	CALU →	-0.621	-0.518	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,729 associations by consensus.

RPS6KA5 vs PPP1R13B — LUAD

Explore this scatter interactively →