RPS6KA4

Across TCGA patient cohorts, RPS6KA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,535 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPS6KA4-associated proteins across cancer lineages are SAMD9, PARP14, and PLCB3. Each is linked with RPS6KA4 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPS6KA4-to-partner and partner-to-RPS6KA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA4 versus SAMD9 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA4→partner) and Y-score (partner→RPS6KA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMD9 →	+0.629	+0.935	<.001	<.001	3	7
OV	PARP14 →	+0.495	+0.538	<.001	<.001	3	7
HNSC	PLCB3 →	+0.433	+0.953	<.001	<.001	3	5
BRCA	IFIH1_S301 →	+0.951	+0.559	<.001	<.001	3	5
HNSC	OASL →	+0.775	+0.938	.001	.001	3	5
BRCA	PURA →	-0.426	-0.601	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,535 associations by consensus.

RPS6KA4 vs SAMD9 — HNSC

Explore this scatter interactively →