RPS6KA4

Across TCGA cell cohorts, RPS6KA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,109 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPS6KA4-associated GO terms across cancer lineages are Peptide antigen transport, Regulation of cell-substrate adhesion, and Regulation of fibroblast proliferation. Each is linked with RPS6KA4 in more than 16 cancer types. Because this analysis shows association rather than direction, both RPS6KA4-to-partner and partner-to-RPS6KA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptide antigen transport grouped by RPS6KA4-low versus RPS6KA4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA4→partner) and Y-score (partner→RPS6KA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peptide antigen transport →	+1.170	+1.477	<.001	<.001	3	17
BONE	Regulation of cell-substrate adhesion →	+0.112	+1.186	<.001	<.001	3	16
OVARY	Regulation of fibroblast proliferation →	+0.113	+1.171	<.001	<.001	3	16
BONE	Protein depolymerization →	+0.169	+2.030	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Establishment or maintenance of cell polarity →	+0.084	+1.151	<.001	.001	3	14
BONE	Regulation of cell-substrate junction assembly →	+0.142	+1.341	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,109 associations by consensus.

Peptide antigen transport by RPS6KA4 expression — BONE

Explore this box plot interactively →