RPS6KA3

Across TCGA patient cohorts, RPS6KA3 RNA expression is significantly associated with the RNA expression of many other genes, with 20,629 significant associations in total. ACC shows the largest number of these associations.

The most reproducible RPS6KA3-associated genes across cancer lineages are MED14, ATP6AP2, and PRR14L. Each is linked with RPS6KA3 in more than 33 cancer types. Because this analysis shows association rather than direction, both RPS6KA3-to-partner and partner-to-RPS6KA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA3 versus MED14 in DLBC, with a Pearson correlation of 0.93.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA3→partner) and Y-score (partner→RPS6KA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	MED14 →	+1.739	+1.839	<.001	<.001	3	34
UVM	ATP6AP2 →	+1.080	+1.386	<.001	<.001	3	34
DLBC	PRR14L →	+1.288	+1.746	<.001	<.001	3	34
UVM	CHM →	+1.426	+1.448	<.001	<.001	3	34
DLBC	SETD2 →	+1.189	+1.289	<.001	<.001	3	34
KIRP	NF1 →	+1.110	+1.170	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,629 associations by consensus.

RPS6KA3 vs MED14 — DLBC

Explore this scatter interactively →