RPS6KA1

Across TCGA patient cohorts, RPS6KA1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,258 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPS6KA1-associated genes across cancer lineages are PARP11, ATP5IF1, and PAFAH2. Each is linked with RPS6KA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPS6KA1-to-partner and partner-to-RPS6KA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA1 versus PARP11 in OV, with a Pearson correlation of -0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA1→partner) and Y-score (partner→RPS6KA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARP11 →	-0.615	-0.264	.006	.005	3	6
UCEC	ATP5IF1 →	+0.615	+0.324	.001	<.001	3	6
BRCA	PAFAH2 →	+0.548	+0.311	<.001	.006	3	6
UCEC	SERINC2 →	+1.279	+0.311	<.001	<.001	3	6
LUAD	CD164L2 →	+0.912	+0.292	<.001	<.001	3	6
HNSC	LYPLA2 →	+0.783	+0.345	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,258 associations by consensus.

RPS6KA1 vs PARP11 — OV

Explore this scatter interactively →