RPS6KA1

Across TCGA cell cohorts, RPS6KA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,147 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPS6KA1-associated GO terms across cancer lineages are Regulation of hepatic stellate cell activation, Positive regulation of hepatic stellate cell activation, and TORC1 signaling. Each is linked with RPS6KA1 in more than 8 cancer types. Because this analysis shows association rather than direction, both RPS6KA1-to-partner and partner-to-RPS6KA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hepatic stellate cell activation grouped by RPS6KA1-low versus RPS6KA1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA1→partner) and Y-score (partner→RPS6KA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of hepatic stellate cell activation →	+0.257	+0.890	.007	<.001	3	9
LUNG_NSCLC_LUAD	Positive regulation of hepatic stellate cell activation →	+0.544	+0.511	<.001	<.001	3	9
URINARY_TRACT	TORC1 signaling →	+0.139	+1.171	<.001	<.001	3	9
SKIN	Actomyosin contractile ring organization →	+0.143	+0.958	<.001	<.001	3	9
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.137	+1.102	<.001	<.001	3	9
STOMACH	Serotonin secretion →	+1.376	+0.971	<.001	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,147 associations by consensus.

Regulation of hepatic stellate cell activation by RPS6KA1 expression — STOMACH

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