RPS5P8

Across TCGA pan-cancer cohorts, RPS5P8 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RPS5P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS5P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS5P8 is over-expressed in tumor, although a few such as HNSC and UCEC show the opposite, repressed pattern.

KIRC, COAD, and KIRP are the cancer types where RPS5P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS5P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.135	<.001	9	view →
COAD	Female	II,III,IV	+2.124	<.001	7	view →
KIRP	Female	II,III,IV	+0.124	.025	4	view →
HNSC	Female	II,III,IV	−0.171	<.001	3	view →
LUAD	All	All	+0.158	.001	3	view →
UCEC	All	IV	−0.645	.038	2	view →
CHOL	All	II,III,IV	+0.370	.033	2	view →
LIHC	All	All	+0.053	.004	2	view →
BLCA	Male	IV	+0.175	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RPS5P8–KIRC

Open the KIRC breakdown →