Across TCGA pan-cancer cohorts, RPS4XP7 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPS4XP7’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where RPS4XP7 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS4XP7 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.
KICH, KIRP, and LIHC are the cancer types where RPS4XP7 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS4XP7 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.