RPS4XP6

Across TCGA pan-cancer cohorts, RPS4XP6 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPS4XP6 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPS4XP6 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPS4XP6 expression acts as an unfavorable survival marker, although some lineages such as LUSC and READ show a favorable association.

LUSC, SARC, and READ are the cancer types where RPS4XP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	II,III,IV	0.706	0.510	.001	46	view →
SARC	OS	Quartile	All	0.424	0.706	<.001	30	view →
READ	DFS	Tertile	II,III,IV	0.665	0.332	.004	28	view →
SKCM	DFS	Median	II,III,IV	0.805	0.610	<.001	28	view →
MESO	DFS	Tertile	IV	0.165	0.552	.001	24	view →
KIRP	DFS	Tertile	All	0.563	0.844	<.001	24	view →
BRCA	OS	Quartile	All	0.948	0.897	.012	18	view →
COAD	OS	Median	IV	0.315	0.639	.016	14	view →
UVM	OS	Tertile	III,IV	1.000	0.185	.016	12	view →
LGG	DFS	Median	All	0.784	0.900	.008	11	view →
ACC	DFS	Quartile	All	0.296	0.677	.013	10	view →
STAD	DFS	Median	III,IV	0.194	0.423	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPS4XP6–LUSC (OS)

Open the LUSC breakdown →