Across TCGA pan-cancer cohorts, RPS4XP4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS4XP4’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where RPS4XP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS4XP4 is over-expressed in tumor.
PAAD, COAD, and KICH are the cancer types where RPS4XP4 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS4XP4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.