RPS4XP23

Across TCGA patient cohorts, RPS4XP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,953 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible RPS4XP23-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, tRNA thio-modification, and IRES-dependent viral translational initiation. Each is linked with RPS4XP23 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPS4XP23-to-partner and partner-to-RPS4XP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by RPS4XP23-low versus RPS4XP23-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS4XP23→partner) and Y-score (partner→RPS4XP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.049	+0.591	<.001	<.001	3	12
PAAD	tRNA thio-modification →	+0.030	+0.315	<.001	<.001	3	12
STAD	IRES-dependent viral translational initiation →	+0.057	+0.264	<.001	<.001	3	11
ESCA	Ribosomal large subunit assembly →	+0.068	+0.293	.005	.002	1	13
ESCA	U4 snRNA 3'-end processing →	+0.040	+0.281	.003	<.001	2	12
ESCA	U2-type prespliceosome assembly →	+0.062	+0.313	.003	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,953 associations by consensus.

Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by RPS4XP23 expression — TGCT

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