RPS4XP20

Across TCGA pan-cancer cohorts, RPS4XP20 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPS4XP20’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPS4XP20 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS4XP20 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

COAD, READ, and KIRP are the cancer types where RPS4XP20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS4XP20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.376	<.001	11	view →
READ	All	All	+0.223	<.001	5	view →
KIRP	All	All	+0.055	.009	5	view →
BLCA	All	III,IV	−0.080	.007	3	view →
KIRC	Male	All	+0.037	.007	3	view →
THCA	All	II,III,IV	+0.107	.043	1	view →
LIHC	All	II,III,IV	+0.045	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPS4XP20–COAD

Open the COAD breakdown →