RPS4XP17

Across TCGA pan-cancer cohorts, RPS4XP17 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPS4XP17’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPS4XP17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS4XP17 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, HNSC, and LIHC are the cancer types where RPS4XP17 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS4XP17 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.921	<.001	10	view →
HNSC	Male	All	+0.236	<.001	8	view →
LIHC	All	All	+0.080	<.001	6	view →
CHOL	All	All	+0.485	<.001	5	view →
LUAD	All	All	+0.222	.001	5	view →
KICH	Female	All	−0.146	.035	2	view →
READ	All	II,III,IV	+0.460	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPS4XP17–COAD

Open the COAD breakdown →