RPS4XP15

Across TCGA pan-cancer cohorts, RPS4XP15 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RPS4XP15 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RPS4XP15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS4XP15 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

KICH, COAD, and KIRP are the cancer types where RPS4XP15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	II,III,IV	0.161	0.827	.004	36	view →
COAD	OS	Tertile	II,III,IV	0.610	0.821	.006	24	view →
KIRP	DFS	Tertile	III,IV	0.264	0.730	.028	18	view →
KIRC	DFS	Tertile	IV	0.291	0.630	.013	18	view →
LUAD	OS	Tertile	III,IV	0.447	0.684	.019	18	view →
STAD	OS	Quartile	III,IV	0.326	0.593	.011	13	view →
UCS	DFS	Median	IV	0.835	0.490	.031	6	view →
LGG	DFS	Tertile	All	0.859	0.721	.031	6	view →
LUSC	DFS	Tertile	All	0.531	0.369	.022	6	view →
ESCA	DFS	Median	All	0.893	0.370	.025	5	view →
OV	OS	Tertile	All	0.269	0.345	.041	4	view →
HNSC	DFS	Tertile	IV	0.760	0.511	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RPS4XP15–KICH (OS)

Open the KICH breakdown →