RPS4XP12

Across TCGA pan-cancer cohorts, RPS4XP12 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS4XP12’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RPS4XP12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS4XP12 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

LUSC, PAAD, and HNSC are the cancer types where RPS4XP12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS4XP12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.074	.001	4	view →
PAAD	Female	All	−0.140	.042	2	view →
HNSC	All	II,III,IV	+0.151	.049	1	view →
LUAD	Female	All	+0.028	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPS4XP12–LUSC

Open the LUSC breakdown →