RPS3AP8

Across TCGA pan-cancer cohorts, RPS3AP8 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS3AP8’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPS3AP8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS3AP8 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

COAD, PAAD, and THCA are the cancer types where RPS3AP8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.099	.024	3	view →
PAAD	Male	All	−0.140	.005	2	view →
THCA	Female	II,III,IV	+0.038	.037	1	view →
KICH	Male	All	+0.026	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPS3AP8–COAD

Open the COAD breakdown →