RPS3AP40

Across TCGA pan-cancer cohorts, RPS3AP40 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPS3AP40’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS3AP40 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS3AP40 is over-expressed in tumor, although a few such as READ and LUAD show the opposite, repressed pattern.

KIRC, READ, and STAD are the cancer types where RPS3AP40 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP40 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.046	.004	6	view →
READ	All	III,IV	−0.150	.017	3	view →
STAD	Female	All	+0.402	.037	2	view →
KIRP	All	IV	+0.070	.030	2	view →
LUAD	All	III,IV	−0.130	.032	1	view →
COAD	Male	II,III,IV	+0.098	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPS3AP40–KIRC

Open the KIRC breakdown →