RPS3AP4

Across TCGA pan-cancer cohorts, RPS3AP4 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPS3AP4 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPS3AP4 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS3AP4 expression acts as an unfavorable survival marker, although some lineages such as LUSC and READ show a favorable association.

LUSC, UCEC, and KIRP are the cancer types where RPS3AP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	II,III,IV	0.686	0.490	<.001	79	view →
UCEC	DFS	Median	All	0.503	0.780	<.001	78	view →
KIRP	OS	Quartile	All	0.471	0.772	<.001	62	view →
READ	DFS	Tertile	All	0.741	0.437	.002	34	view →
SARC	OS	Quartile	All	0.603	0.859	.001	19	view →
BRCA	DFS	Tertile	III,IV	0.956	0.852	.006	13	view →
ESCA	OS	Tertile	IV	0.713	0.143	.024	13	view →
OV	OS	Quartile	III,IV	0.288	0.392	.020	10	view →
LGG	OS	Median	All	0.931	0.844	.007	9	view →
CESC	DFS	Quartile	IV	0.217	0.569	.036	6	view →
THCA	DFS	Quartile	All	0.933	0.807	.014	5	view →
SKCM	OS	Tertile	All	0.821	0.752	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPS3AP4–LUSC (DFS)

Open the LUSC breakdown →