RPS3AP39

Across TCGA pan-cancer cohorts, RPS3AP39 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPS3AP39’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPS3AP39 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS3AP39 is over-expressed in tumor, although a few such as THCA and PAAD show the opposite, repressed pattern.

THCA, COAD, and STAD are the cancer types where RPS3AP39 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP39 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.197	<.001	6	view →
COAD	All	All	+0.137	.015	4	view →
STAD	All	II,III,IV	+0.239	.012	2	view →
PAAD	Female	All	−0.130	.049	2	view →
KIRP	All	II,III,IV	−0.040	.017	2	view →
KICH	Male	All	+0.067	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPS3AP39–THCA

Open the THCA breakdown →