RPS3AP35

Across TCGA pan-cancer cohorts, RPS3AP35 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RPS3AP35 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RPS3AP35 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPS3AP35 expression acts as an unfavorable survival marker, although some lineages such as LGG and GBM show a favorable association.

THCA, COAD, and LGG are the cancer types where RPS3AP35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.813	0.932	<.001	83	view →
COAD	DFS	Tertile	II,III,IV	0.202	0.497	.001	45	view →
LGG	OS	Median	All	0.939	0.852	<.001	31	view →
UCS	DFS	Tertile	All	0.317	0.586	.011	26	view →
STAD	DFS	Tertile	II,III,IV	0.558	0.705	.011	18	view →
GBM	DFS	Quartile	All	0.464	0.150	<.001	15	view →
LUSC	OS	Quartile	III,IV	0.224	0.870	<.001	14	view →
BRCA	DFS	Tertile	All	0.872	0.908	.028	12	view →
ESCA	DFS	Tertile	All	0.232	0.436	.009	12	view →
BLCA	DFS	Tertile	IV	0.150	0.486	.011	9	view →
DLBC	OS	Tertile	IV	0.147	1.000	.045	9	view →
READ	OS	Tertile	All	0.830	0.938	.049	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RPS3AP35–THCA (DFS)

Open the THCA breakdown →