Across TCGA pan-cancer cohorts, RPS3AP32 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPS3AP32’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPS3AP32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS3AP32 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
COAD, BRCA, and LUSC are the cancer types where RPS3AP32 tumor–normal differential expression is most reproducible.