RPS3AP3

Across TCGA pan-cancer cohorts, RPS3AP3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RPS3AP3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RPS3AP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS3AP3 is over-expressed in tumor.

BLCA, LUSC, and COAD are the cancer types where RPS3AP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.352	<.001	8	view →
LUSC	Male	II,III,IV	+0.432	<.001	7	view →
COAD	All	All	+0.292	.001	5	view →
HNSC	All	II,III,IV	+0.074	.020	5	view →
STAD	All	All	+0.338	.001	4	view →
BRCA	All	All	+0.223	.001	4	view →
LUAD	All	IV	+0.470	.007	3	view →
UCEC	All	IV	+0.915	.024	2	view →
ESCA	All	All	+0.483	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RPS3AP3–BLCA

Open the BLCA breakdown →