Q-omics provides the consensus-scored RPS3AP27 profile across patient tissues and cancer cell-line models. RPS3AP27 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RPS3AP27 is differentially expressed in 6, with the highest sampling consensus in COAD. Additionally, RPS3AP27 RNA expression shows 9,726 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight KIRC, COAD, and KIRP as cancer lineages where RPS3AP27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS3AP27 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS3AP27 survival associations across molecular data types. RPS3AP27 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS3AP27 RNA expression–survival associations across cancer types. High RPS3AP27 expression shows unfavorable associations in KIRC, BLCA and ACC, but favorable associations in UCS, BRCA and MESO. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify KIRC as the clearest survival context for RPS3AP27 RNA expression.
This table summarizes RPS3AP27 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RPS3AP27. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS3AP27 shows lower tumor expression in THCA, KIRP and LUAD and higher tumor expression in COAD, HNSC and KIRC. The COAD box plot shows higher RPS3AP27 RNA expression in tumor versus normal tissue (log2 FC = +0.212, t-test p < 0.001).
This table shows molecular features associated with RPS3AP27 in patient tissues and cancer cell lines. In patient samples, RPS3AP27 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
