RPS3AP25

Across TCGA pan-cancer cohorts, RPS3AP25 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPS3AP25’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPS3AP25 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS3AP25 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, COAD, and UCEC are the cancer types where RPS3AP25 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP25 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.182	<.001	6	view →
COAD	All	II,III,IV	+0.262	.028	3	view →
UCEC	All	All	−0.596	.002	2	view →
CHOL	All	All	+0.273	.008	2	view →
LIHC	Female	III,IV	+0.224	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPS3AP25–BRCA

Open the BRCA breakdown →