Across TCGA pan-cancer cohorts, RPS3AP23 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPS3AP23’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPS3AP23 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS3AP23 is over-expressed in tumor.

HNSC and LUSC are the cancer types where RPS3AP23 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP23 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.028	.007	7	view →
LUSC	All	All	+0.032	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RPS3AP23 RNA expression & survival · all RPS3AP23 data types