RPS3AP18

Across TCGA pan-cancer cohorts, RPS3AP18 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPS3AP18’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RPS3AP18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS3AP18 is over-expressed in tumor, although a few such as ESCA and BRCA show the opposite, repressed pattern.

LUAD, HNSC, and KIRC are the cancer types where RPS3AP18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.476	<.001	8	view →
HNSC	Male	III,IV	+0.250	.012	7	view →
KIRC	Male	All	+0.147	.001	6	view →
ESCA	Female	All	−1.050	.011	2	view →
BRCA	All	IV	−0.369	.033	2	view →
LUSC	Male	All	+0.192	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPS3AP18–LUAD

Open the LUAD breakdown →