RPS3AP16

Across TCGA pan-cancer cohorts, RPS3AP16 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPS3AP16 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RPS3AP16 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS3AP16 expression acts as an unfavorable survival marker, although some lineages such as COAD and MESO show a favorable association.

ACC, UCEC, and COAD are the cancer types where RPS3AP16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	II,III,IV	0.289	0.785	<.001	69	view →
UCEC	DFS	Median	II,III,IV	0.245	0.695	.001	50	view →
COAD	DFS	Quartile	II,III,IV	0.835	0.436	.004	42	view →
KIRP	DFS	Tertile	IV	0.034	0.527	<.001	38	view →
KICH	OS	Tertile	III,IV	0.190	0.763	.001	37	view →
MESO	DFS	Tertile	All	0.686	0.330	.007	24	view →
DLBC	OS	Median	II,III,IV	0.447	0.865	.003	22	view →
CHOL	OS	Tertile	All	0.136	0.710	.005	18	view →
LIHC	OS	Tertile	III,IV	0.477	0.686	.021	18	view →
THCA	DFS	Tertile	III,IV	0.947	0.319	.009	17	view →
LUSC	DFS	Tertile	All	0.718	0.590	.010	13	view →
SKCM	DFS	Median	All	0.702	0.581	.020	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPS3AP16–ACC (OS)

Open the ACC breakdown →