RPS3A

Across TCGA pan-cancer cohorts, RPS3A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RPS3A data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RPS3A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RPS3A expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and SKCM are the cancer types where RPS3A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.158	0.835	<.001	32	view →
UCEC	DFS	Median	II,III,IV	1.000	0.438	.016	32	view →
SKCM	OS	Median	III,IV	0.233	0.705	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RPS3A–LUAD (OS)

Open the LUAD breakdown →