Across TCGA pan-cancer cohorts, RPS2P6 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPS2P6’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS2P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS2P6 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
KIRC, COAD, and HNSC are the cancer types where RPS2P6 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS2P6 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.