RPS2P5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPS2P5 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RPS2P5 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RPS2P5 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPS2P5 expression acts as an unfavorable survival marker, although some lineages such as UVM and GBM show a favorable association.

UVM, KIRP, and ACC are the cancer types where RPS2P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileII,III,IV0.8020.327<.00193view →
KIRPDFSTertileAll0.8240.969<.00189view →
ACCDFSMedianAll0.2760.613<.00174view →
GBMDFSTertileAll0.3560.190.00232view →
OVOSTertileII,III,IV0.2630.383.00328view →
LIHCOSMedianAll0.7250.822.01725view →
COADDFSMedianAll0.6660.323<.00124view →
STADDFSMedianII,III,IV0.5720.278.00114view →
MESOOSTertileIV0.2770.818.00612view →
THCADFSMedianIV0.4370.865.0019view →
SARCOSTertileAll0.4020.570.0059view →
READOSMedianIV0.4660.824.0069view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RPS2P5–UVM (OS)

Kaplan–Meier survival curve for RPS2P5 RNA-high vs -low samples in UVM.

Open the UVM breakdown →

Exploration