RPS28

Across TCGA cell cohorts, RPS28 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,673 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPS28-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, Regulation of amyloid fibril formation, and Cytoplasm protein quality control by the ubiquitin-proteasome system. Each is linked with RPS28 in more than 9 cancer types. Because this analysis shows association rather than direction, both RPS28-to-partner and partner-to-RPS28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by RPS28-low versus RPS28-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS28→partner) and Y-score (partner→RPS28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	[4Fe-4S] cluster assembly →	+0.166	+1.033	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of amyloid fibril formation →	-0.119	-0.566	.001	.001	3	9
BLOOD_Lymphoma	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.120	+0.518	<.001	.001	3	9
BONE	Negative regulation of transcription initiation-coupled chromatin remodeling →	+0.129	+0.697	.002	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytokine-mediated signaling pathway →	-0.111	-0.715	.004	<.001	3	8
BLOOD_Leukemia	Cytoskeleton-dependent cytokinesis →	-0.055	-0.568	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,673 associations by consensus.

[4Fe-4S] cluster assembly by RPS28 expression — BREAST

Explore this box plot interactively →