RPS27P27

Across TCGA pan-cancer cohorts, RPS27P27 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPS27P27’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS27P27 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS27P27 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

KIRC, THCA, and STAD are the cancer types where RPS27P27 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS27P27 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.094	.002	7	view →
THCA	All	II,III,IV	+0.127	.013	3	view →
STAD	Male	III,IV	−0.335	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPS27P27–KIRC

Open the KIRC breakdown →