RPS27P22

Across TCGA pan-cancer cohorts, RPS27P22 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPS27P22’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RPS27P22 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS27P22 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

UCEC, BRCA, and KIRP are the cancer types where RPS27P22 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS27P22 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.117	.030	2	view →
BRCA	All	III,IV	+0.076	.028	2	view →
KIRP	All	All	−0.059	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPS27P22–UCEC

Open the UCEC breakdown →