RPS27P20

Across TCGA pan-cancer cohorts, RPS27P20 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPS27P20’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPS27P20 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS27P20 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC and LUAD are the cancer types where RPS27P20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS27P20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	−0.064	.015	2	view →
LUAD	All	All	+0.112	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPS27P20–HNSC

Open the HNSC breakdown →