Q-omics provides the consensus-scored RPS27P15 profile across patient tissues and cancer cell-line models. RPS27P15 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, RPS27P15 is differentially expressed in 8, with the highest sampling consensus in HNSC. Additionally, RPS27P15 RNA expression shows 8,664 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight HNSC, and TGCT as cancer lineages where RPS27P15 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS27P15 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS27P15 survival associations across molecular data types. RPS27P15 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS27P15 RNA expression–survival associations across cancer types. High RPS27P15 expression shows unfavorable associations in MESO, DLBC, KICH and STAD, but favorable associations in HNSC and LUAD. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify HNSC as the clearest survival context for RPS27P15 RNA expression.
This table summarizes RPS27P15 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPS27P15. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS27P15 shows higher tumor expression in HNSC, READ, PAAD, COAD, LUAD and PRAD. The HNSC box plot shows higher RPS27P15 RNA expression in tumor versus normal tissue (log2 FC = +0.077, t-test p = .030).
This table shows molecular features associated with RPS27P15 in patient tissues and cancer cell lines. In patient samples, RPS27P15 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
