RPS27P14

Across TCGA pan-cancer cohorts, RPS27P14 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPS27P14’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS27P14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS27P14 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

KIRC, UCEC, and LUAD are the cancer types where RPS27P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS27P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.119	<.001	6	view →
UCEC	All	IV	−0.620	.002	2	view →
LUAD	Female	All	+0.232	.011	2	view →
COAD	Male	II,III,IV	+0.105	.045	2	view →
THCA	Female	II,III,IV	+0.164	.038	1	view →
LIHC	All	All	+0.042	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPS27P14–KIRC

Open the KIRC breakdown →