Across TCGA patient cohorts, RPS27L mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS27L-associated genes across cancer lineages are RNU6-271P, AQP7P4, and LINC01670. Each is linked with RPS27L in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS27L-to-partner and partner-to-RPS27L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS27L→partner) and Y-score (partner→RPS27L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-271P →	+0.431	+4.267	<.001	.009	3	2
UCEC	AQP7P4 →	+0.076	+4.442	<.001	.007	3	1
UCEC	LINC01670 →	+0.215	+4.258	<.001	.003	3	1
UCEC	MIR3193 →	+1.546	+4.838	<.001	<.001	3	1
UCEC	WBP1LP6 →	+0.206	+5.660	<.001	.001	3	1
BLCA	MTCO3P19 →	+0.150	+5.177	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

RPS27L survival (RNA) · tumor vs normal (RNA) · all RPS27L data types