RPS27AP5

Across TCGA patient cohorts, RPS27AP5 protein abundance is significantly associated with the RNA expression of many other genes, with 429 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPS27AP5-associated genes across cancer lineages are SPINT3, GZMK, and DUSP26. Each is linked with RPS27AP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS27AP5-to-partner and partner-to-RPS27AP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS27AP5 versus SPINT3 in PDAC, with a Pearson correlation of -0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS27AP5→partner) and Y-score (partner→RPS27AP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SPINT3 →	-0.183	-1.235	<.001	.001	3	1
PDAC	GZMK →	+1.140	+1.014	.003	.008	3	1
PDAC	DUSP26 →	-0.736	-1.014	.002	.008	3	1
PDAC	SLC25A52 →	-0.209	-1.014	.006	.008	3	1
PDAC	CCDC25 →	+0.438	+1.014	<.001	.008	3	1
PDAC	SLC25A30 →	+0.521	+1.014	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 429 associations by consensus.

RPS27AP5 vs SPINT3 — PDAC

Explore this scatter interactively →