Across TCGA pan-cancer cohorts, RPS27AP16 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RPS27AP16 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RPS27AP16 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS27AP16 expression acts as an unfavorable survival marker, although some lineages such as THCA and KIRC show a favorable association.

KIRP, ACC, and UCEC are the cancer types where RPS27AP16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.545	0.938	<.001	121	view →
ACC	DFS	Median	All	0.216	0.687	<.001	121	view →
UCEC	DFS	Median	All	0.530	0.802	<.001	84	view →
LIHC	OS	Quartile	All	0.573	0.805	<.001	54	view →
LUAD	OS	Quartile	All	0.744	0.870	.003	52	view →
THCA	OS	Median	All	0.996	0.958	.003	51	view →
KIRC	DFS	Quartile	All	0.700	0.496	.002	39	view →
LGG	DFS	Median	All	0.878	0.783	<.001	35	view →
BLCA	DFS	Median	All	0.560	0.453	.010	27	view →
LUSC	DFS	Quartile	All	0.545	0.272	<.001	23	view →
BRCA	DFS	Tertile	II,III,IV	0.923	0.961	.004	19	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration

Same gene, other analysis: RPS27AP16 tumor-vs-normal RNA expression · all RPS27AP16 data types