Across TCGA pan-cancer cohorts, RPS27AP14 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPS27AP14’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where RPS27AP14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS27AP14 is over-expressed in tumor.
KICH are the cancer types where RPS27AP14 tumor–normal differential expression is most reproducible.