RPS27AP10

Across TCGA pan-cancer cohorts, RPS27AP10 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPS27AP10 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPS27AP10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS27AP10 expression acts as an unfavorable survival marker, although some lineages such as ACC and LAML show a favorable association.

UCEC, BLCA, and ACC are the cancer types where RPS27AP10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	IV	0.279	0.604	.021	36	view →
BLCA	DFS	Quartile	IV	0.223	0.553	.003	35	view →
ACC	DFS	Tertile	II,III,IV	0.767	0.314	.010	29	view →
LUAD	DFS	Median	IV	0.326	0.665	.006	25	view →
LAML	DFS	Tertile	All	0.735	0.291	<.001	24	view →
STAD	DFS	Median	IV	0.200	0.642	.012	21	view →
COAD	DFS	Median	II,III,IV	0.330	0.593	.008	19	view →
PCPG	OS	Tertile	All	0.596	0.982	.002	15	view →
DLBC	DFS	Median	II,III,IV	0.580	1.000	.013	15	view →
THCA	OS	Tertile	III,IV	0.885	0.985	.008	12	view →
KICH	DFS	Quartile	II,III,IV	0.430	0.820	.006	11	view →
CHOL	DFS	Tertile	III,IV	0.163	0.529	.024	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPS27AP10–UCEC (OS)

Open the UCEC breakdown →