RPS27A

Across TCGA pan-cancer cohorts, RPS27A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RPS27A data layer compared with 26 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RPS27A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RPS27A expression acts as an unfavorable survival marker.

OV, HNSC, and BLCA are the cancer types where RPS27A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.010	0.844	<.001	36	view →
HNSC	OS	Median	All	0.187	0.768	<.001	36	view →
BLCA	OS	Median	All	0.059	0.720	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RPS27A–OV (OS)

Open the OV breakdown →