RPS27A

Across TCGA cell cohorts, RPS27A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,507 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPS27A-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Formation of translation preinitiation complex, and Pentose-phosphate shunt, non-oxidative branch. Each is linked with RPS27A in more than 13 cancer types. Because this analysis shows association rather than direction, both RPS27A-to-partner and partner-to-RPS27A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by RPS27A-low versus RPS27A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS27A→partner) and Y-score (partner→RPS27A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of protein-containing complex assembly →	-0.084	-0.663	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Formation of translation preinitiation complex →	+0.141	+1.019	<.001	<.001	3	13
LIVER	Pentose-phosphate shunt, non-oxidative branch →	+0.129	+0.531	.003	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of establishment of protein localization →	-0.048	-0.773	.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein transport →	-0.066	-1.079	.002	<.001	3	13
BONE	Regulation of purine nucleotide metabolic process →	-0.075	-0.800	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,507 associations by consensus.

Negative regulation of protein-containing complex assembly by RPS27A expression — BONE

Explore this box plot interactively →