RPS27A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RPS27A protein abundance is significantly associated with the RNA expression of many other genes, with 544 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPS27A-associated genes across cancer lineages are NMD3, EIF1B, and DMAC2. Each is linked with RPS27A in more than 2 cancer types. Because this analysis shows association rather than direction, both RPS27A-to-partner and partner-to-RPS27A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS27A versus NMD3 in BONE, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS27A→partner) and Y-score (partner→RPS27A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENMD3 →+0.602+1.195.007.00333
BLOOD_LeukemiaEIF1B →+0.896+1.736.007.00133
CNSDMAC2 →+0.437+1.386<.001<.00132
CNSVAMP8 →-2.265-1.386.007<.00132
CNSZNF628 →+0.598+1.386<.001<.00132
BLOOD_MyelomaNCOA3 →+1.419+1.436.009.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 544 associations by consensus.

RPS27A vs NMD3 — BONE

Per-sample scatter of RPS27A vs NMD3 in BONE (Pearson r = 0.85).

Explore this scatter interactively →

Exploration